规格

20ug

编号

CZDB-015

价格

询价

中文名

Mouse / Human / Rat BDNF Protein /重组小鼠/大鼠/人

分子别称

BDNF

分子种属

Mouse

表达标签

His，S

表达宿主

E. coli

浓度

> 95 % as determined by SDS-PAGE

缓冲液

Lyophilized from sterile PBS, pH 7.4

存储条件

-70°C，应避免反复冻融。

基本描述

BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.