KYDFYDBT
β淀粉样蛋白肽
β淀粉样蛋白肽
β淀粉样蛋白肽
β淀粉样蛋白是一种与阿尔茨海默病(AD)有关的蛋白,其在患者大脑中堆积形成的淀粉样斑块的蛋白。β淀粉样蛋白肽通常含有39~43 个氨基酸。在神经退行性疾病状态下,经β分泌酶和γ分泌酶依次酶解淀粉样前体蛋白(APP:一种 100-140 kDa 的跨膜糖蛋白)而产生的不溶性低聚物,最终导致神经元死亡。由于β-淀粉样蛋白(Aβ40/42)在AD发病中起关键作用,因而成为AD的蛋白免疫疗法项目中研究较多的蛋白之一。
存货编码 名称 三字母序列 单字母序列
04010002402 β-Amyloid (25-35) H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH (trifluoroacetate salt) GSNKGAIIGLM
04010011526 β-Amyloid (1-42),human H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH (trifluoroacetate salt) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
04010011540 β-Amyloid(1-40),rat Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV
04010011827 β-Amyloid (1-42),rat Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
04010011521 β-Amyloid(1-40),human H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH (trifluoroacetate salt) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV